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(i) Prospective Financial Statements If the presentation does not meet the minimum disclosure requirement of prospective nancial statements [see Subsection 401(a)], it is a partial presentation rather than prospective nancial statements In that case, the accountant is not required to provide a standard service on the prospective data 23 of the AICPA Guide contains guidelines for compilations, examinations, and application of agreed-upon procedures to partial presentations It does not require those services on partial presentations, but provides guidance for the accountant who is engaged to provide them (ii) Third-Party Use Third parties generally are any persons outside the entity presenting the prospective nancial statements Sometimes, however, such persons may not need to be considered third parties for the purpose of determining whether the guidance on accountants services applies The AICPA Guide (Section 1002) provides the following guidelines for determining whether outsiders are considered third parties: In deciding whether a party that is or reasonably might be expected to use an accountant s report is considered to be a third party, the accountant should consider the degree of consistency of interest between [management] and the user regarding the forecast If their interests are substantially consistent (eg, both the [preparer] and the user are employees of the entity about which the forecast is made), the user would not be deemed to be a third party On the other hand, where the interests of the [preparer] and user are potentially inconsistent (eg, the [preparer] is a nonowner manager and the user is an absentee owner), the user would be deemed a third party In some cases, this determination will require the exercise of considerable professional judgment In considering whether the statements will be restricted to internal use, the accountant may generally rely on management s oral or written representations, unless something leads the accountant to believe that, despite management s representations, the statements are likely to be distributed to a third party (iii) Assemble and Submit Assembly means the manual or computer processing of mathematical or other clerical functions related to the presentation of the prospective nancial statements (AICPA Guide, Section 316) This refers to converting the assumptions into prospective amounts or putting the amounts into the form of statements Assembly does not mean merely copying or collating statements prepared by someone else (c) INTERNAL USE The accountant may provide compilation, examination, or agreed-upon procedures engagements for internal use if engaged to do so However, for internal use, the accountant has more exibility to accommodate the varying circumstances of the engagement Normally, these engagements involve consulting or planning (such as in management-consulting or tax-planning services) rather than third-party reliance Common reporting options for internal use include assembly reports and lain paper prospective nancial statements Internal-use services are discussed in more detail in Section 409 (d) PROHIBITED ENGAGEMENTS The AICPA Guide prohibits the accountant from submitting or reporting on prospective nancial statements intended for third-party use if those statements omit the disclosure of signi cant assumptions Similarly, the accountant is prohibited from submitting or reporting on a projection for third-party use if it does not identify the hypothetical assumption or describe the limitations on the usefulness of the presentation The accountant also may not submit or report on a nancial projection that is intended for general use (unless it supplements a forecast for the same period) because such use is considered inappropriate [see Subsection 402(b)] This prohibition means that the accountant could not assemble and submit such a presentation even if management agreed not to present the accountant s report or refer to the accountant in the document containing the projection that would be presented to general users.

In these two experimental infections, cidofovir was highly effective in reducing viral replication and lesion development.27 Collectively these data indicate that CDV is able to signi cantly reduce mortality in mice exposed to VV or CV when given as late as 96 h postinoculation. For protection from death, CDV can be reduced to one single dose or one to three smaller doses. Protection from infection can also be conferred by pretreatment with CDV as early as 5 days prior to exposure. The results obtained for SCID mice suggest that long-term treatments may be necessary for protecting immunocompromised individuals. These collective results have major implications, as they suggest that CDV, in addition to being effective as a treatment for smallpox or vaccine complications, can be used for pre- or postexposure prophylaxis of smallpox contacts (i.e., ring treatment) and that a single dose may provide signi cant protection. From these data it is clear that the effect of CDV is long lasting and may translate to short-term or single-dose treatment for smallpox or other orthopoxvirus infections. 14.4 ACYCLIC NUCLEOSIDE PHOSPHONATE ANALOGUES. Make Barcode In .NET Using Barcode maker for Visual . In Visual C#.NET Using Barcode drawer for .Related: 

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(a) SCOPE OF THE COMPILATION SERVICE A compilation of prospective nancial statements is similar to a compilation of historical nancial statements performed subject to SSARS No 1, Compilation and Review of Financial Statements (1978) It relies primarily on an informed reading of the statements with an eye for obvious problems, but it does not provide any assurance on the statements The AICPA Guide states that a compilation of prospective nancial statements involves these three: 1 Assembling, to the extent necessary, the prospective nancial statements based on management s assumptions 2 Performing the required compilation procedures, including reading the prospective nancial statements with their summaries of signi cant assumptions and accounting policies and considering whether they appear to be presented in conformity with AICPA presentation guidelines and not obviously inappropriate 3 Issuing a compilation report (b) ASSEMBLY Assembly, which is e ned in Subsection 405(b)(iii), refers to performing the necessary mathematics to turn assumptions into prospective nancial data and drafting prospective nancial statements in the appropriate form In some cases, such as when the client has a sophisticated nancial reporting function and prepares its own statements, assembly may not be required in a compilation Often, however, assembly assistance is one of the primary bene ts the client receives from the accountant Assembly does not include identifying key factors or developing assumptions, although accountants often help clients in these areas in a compilation (c) COMPILATION PROCEDURES The compilation procedures required by AICPA standards are listed in Exhibit 404 There are two principal differences between the procedures done in a compilation of prospective statements and a compilation of historical statements: the requirement to consider the actual results for any expired portion of the prospective period and the requirement to obtain signed representations from the client Another difference between prospective and historical compilations is that working papers are required in a compilation of prospective nancial statements The working papers serve mainly to:.

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; Arora, V; Barklis, E; Hill, A; Smith, A; Wallace, R Rapid development of an ntisense phosphorodiamidate morpholino oligomer for the treatment of West Nile virus Antiviral Res 2004, 62, A32 A33 274 Shi, P Y; Tilgner, M; Lo, M K Construction and characterization of subgenomic replicons of New York strain of West Nile virus Virology 2002, 296, 219 233 275 Shi, P Y; Tilgner, M; Lo, M K; Kent, K A; Bernard, K A Infectious cDNA clone of the epidemic West Nile virus from New York City J Virol 2002, 76, 5847 5856 276 Lo, M K; Tilgner, M; Shi, P Y Potential high-throughput assay for screening inhibitors of West Nile virus replication J Virol 2003, 77, 12901 12906 277 Shi, P Y Strategies for the identi cation of inhibitors of West Nile virus and other aviviruses.

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Curr Opin Invest Drugs 2002, 3, 1567 1573 278 Sidwell, R W; Smee, D F Viruses of the Bunya- and Togaviridae families: potential as bioterrorism agents and means of control Antiviral Res 2003, 57, 101 111 279 Perez, L; Carrasco, L Involvement of the vacuolar H -ATPase in animal virus entry J Gen Virol 1994, 75, 2595 2606 280 Perez, L; Carrasco, L Entry of poliovirus into cells does not require a low-pH step J Virol 1993, 67, 4543 4548 281 Guinea, R; Carrasco, L Concanamycin-A a powerful inhibitor of enveloped animalvirus entry into cells Biochem Biophys Res Commun 1994, 201, 1270 1278 282 Irurzun, A; Nieva, J L; Carrasco, L Entry of Semliki Forest virus into cells: effects of concanamycin A and nigericin on viral membrane fusion and infection Virology 1997, 227, 488 492 283 Jahrling, P B; Hesse, R A.

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